ACP Journal Club. Review: Routine venous thromboembolism prophylaxis in hospitalized frail older patients has uncertain benefit.

Venous thromboembolism prophylaxis in hospitalized patients: a clinical practice guideline from the American College of Physicians.

DESCRIPTION The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on prophylaxis of venous thromboembolism for hospitalized nonsurgical patients (medical patients and patients with acute stroke). METHODS This guideline is based on published literature on the topic from 1950 through April 2011 that was identified by using...

Routine pharmacological venous thromboembolism prophylaxis in frail older hospitalised patients: where is the evidence?

It has been claimed that there are over 25,000 preventable in-hospital deaths from venous thromboembolism annually in the UK. NICE and SIGN guidelines therefore recommend that all hospitalised patients are risk assessed for venous thromboembolism. The guidelines would recommend using pharmacological thromboprophylaxis for all patients aged 60 and above with reduced mobility and acute medical il...

Review: Long-term anticoagulation reduces recurrent venous thromboembolism.

Review: exercise interventions reduce length and cost of hospital stay in older patients hospitalized for acute conditions.

M e t h o d s Data sources: MEDLINE, EMBASE/ Excerpta Medica, CINAHL, Current

Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients.

BACKGROUND Underutilization of anticoagulant prophylaxis may be due to lack of evidence that prophylaxis prevents clinically important outcomes in hospitalized medical patients at risk for venous thromboembolism. PURPOSE To assess the effects of anticoagulant prophylaxis in reducing clinically important outcomes in hospitalized medical patients. DATA SOURCES MEDLINE, EMBASE, and Cochrane da...